A Potential New Hope for Patients with Chronic CNS Symptoms – Haduvio™

Are you suffering from or caring for someone with symptoms associated with chronic neurologically mediated conditions?

Trevi is developing Haduvio™ (nalbuphine ER) as an oral treatment for a range of indications for which patients have few, if any, treatment options. With its dual mechanism of action, Haduvio™ has the potential to significantly improve the quality of life of patients with a broad range of neurologically mediated conditions.

For what indications is Haduvio™ being developed?
We are currently investigating the use of Haduvio™ in patients with:

    • Prurigo Nodularis – a chronic, intensely pruritic dermatological condition characterized by the presence of pruriginous lesions such as papules, nodules or plaques, which may be associated with excoriations and ulcerations.
    • Pruritus in Chronic Liver Disease – a common complication of chronic cholestatic liver diseases such as primary biliary cholangitis (PBC) and primary sclerosing cholangitis (PSC); patients develop severe whole-body itch, an intense, intractable, debilitating condition that significantly disrupts patients’ daily activities and sleep, and consequently impairs their quality of life.
    • Chronic Cough related to Idiopathic Pulmonary Fibrosis (IPF) – IPF is a rare, chronic, progressive lung disease, characterized by scarring and thickening of lung tissue; most patients diagnosed with IPF suffer from a dry, non-productive chronic cough that interrupts their daily living and significantly contributes to poor quality of life.

And are planning future clinical trials in patients with:

    • Levodopa-induced Dyskinesia (LID) in patients with Parkinson’s Disease – involuntary / motor complications resulting from levodopa therapy.
How can I stay informed on progress being made with Haduvio™?
Please visit our News page for the latest Trevi developments.

You can also follow our clinical progress on the www.clinicaltrials.gov website by typing Trevi Therapeutics into the “Other terms” search box.

How can I get involved in a clinical trial?
Email us at: admin@trevitherapeutics.com

Interested in the PRISM Study? Click:  https://theprismstudy.com to take a short Pre-Qualifying questionnaire.

Contact your physician to inquire about clinical trials available in your area.

Note: Haduvio™ is still investigational and not yet approved for use.